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科学研究

编辑:系统管理员 发布日期:2014-03-05 来源:新闻宣传中心

近五年发表的SCI论文

1) Alber J, Jiang L, Geyer J (2013) CaRch1p does not functionally interact with the high-affinity Ca2+ influx system (HACS) of Candida albicans. Yeast (IF2.0) (http://onlinelibrary.wiley.com/doi/10.1002/yea.2981/abstract)

2) Liu N, Fan F, Qiu D, Jiang L* (2013) The transcription cofactor FgSwi6 plays a role in growth and development, carbendazim sensitivity, cellulose utilization, lithium tolerance, deoxynivalenol production and virulence in the filamentous fungus Fusarium graminearum. Fungal and Genetic Biology 58-59:42-52. (IF3.3)

3) Zhao Y, Du J, Xiong B, Xu H, Jiang L* (2013) ESCRT components regulate the expression of the ER/Golgi calcium pump gene PMR1 through the Rim101/Nrg1 pathway in budding yeast. Journal of Molecular Cell Biology 5(5):336-344. (IF7.3)

4) Xu G, Chen X, Liu L*, Jiang L (2013) Fumaric acid production in Saccharomyces cerevisiae by simultaneous use of oxidative and reductive routes. Bioresource Technology 148:91-96 (IF4.8)

5) Liu T, Wang Y, Baker GM, Fahmy H, Jiang L and Xue C* (2013) The glucose sensor-like protein Hxs1 is a high-affinity glucose transporter and required for virulence in Cryptococcus neoformans. Plos ONE 8(5): e64239. (IF 3.7)

6) Zhao Y, Du J, Zhao G, Jiang L* (2013) Activation of calcineurin is mainly responsible for the calcium sensitivity of gene deletion mutations in the genome of budding yeast. Genomics 101(1): 49-56 (IF3.0)

7) Zhang L, Liu N, Ma X, Jiang L* (2013) The transcriptional control machinery as well as the cell wall integrity and its regulation are involved in the detoxification of the organic solvent dimethyl sulfoxide in Saccharomyces cerevisiae. FEMS Yeast Research 13(2):200-218 (IF2.5)

8) Feng J, Zhao Y, Duan Y, Jiang L* (2013) Genetic interactions between protein phosphatases CaPtc2p and CaPph3p in response to genotoxins and rapamycin in Candida albicans. FEMS Yeast Research 13(1):85-96 (IF2.5)

9) Xu G, Zou W, Chen X, Xu N, Liu L*, Chen J* (2012) Fumaric acid production in Saccharomyces cerevisiae by in silico aided metabolic engineering. PLoS One 7(12): e52086 (IF4.092)

10) Zhao Y, Feng J, Li J, Jiang L* (2012) Mithochondrial type 2C protein phosphatases CaPtc5p, CaPtc6p, and CaPtc7p play vital roles in cellular responses to antifungal drugs and cadmium in Candida albicans. FEMS Yeast Research 12 (8): 897-906 (IF2.5)

11) Jiang L*, Alber J, Wang J, Du W, Li X, Geyer J (2012) The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic Ca2+ homoeostasis. Biochemical Journal 444(3): 497-502 (IF4.7)

12) Xu G, Hua Q, Duan N, Liu L*, Chen J (2012) Regulation of thiamine synthesis in Saccharomyces cerevisiae for improved pyruvate production. Yeast 29(6): 209-217 (IF1.9)

13) Xu G, Liu L*, Chen J* (2012) Reconstruction of cytosolic fumaric acid biosynthetic pathways in Saccharomyces cerevisiae. Microb Cell Fact 11: 24 (IF3.6)

14) Wang Y, Liu TB, Patel S, Jiang L*, Xue C* (2011) The casein kinase I Cck1 regulates multiple signaling pathways and is essential for cell integrity and fungal virulence in Cryptococcus neoformans. Eukaryotic Cell 10(11): 1455–1464 (IF3.6)

15) Feng J, Zhao J, Li J, Zhang L, Jiang L* (2010) Functional characterization of the PP2C phosphatase CaPtc2p in the human fungal pathogen Candida albicans. Yeast 27(9):753-64 (IF2.0)

16) Zhao J, Lin W, Ma X, Lu, Q, Ma X, Bian G, Jiang L* (2010) The protein kinase Hal5p is the high-copy suppressor of lithium-sensitive mutations of genes involved in sporulation and meiosis as well as ergosterol biosynthesis in Saccharomyces cerevisiae. Genomics 95(5): 290-298 (IF3.0)

17) Li X, Du W, Zhao J, Zhang L, Zhu Z, Jiang L* (2010) The MAP kinase-activated protein kinase Rck2p regulates cellular responses to cell wall stresses, filamentation and virulence in the human fungal pathogen Candida albicans. FEMS Yeast Research 10(4): 441-451 (IF2.5)

18) Liu W, Zhao J, Li X, Li Y, Jiang L* (2010) The protein kinase CaSch9p is required for the cell growth, filamentation and virulence in the human fungal pathogen Candida albicans. FEMS Yeast Research 10(4): 462-470 (IF2.5)

19) Jiang L*, Zhao J, Guo R, Li J, Yu L, Xu D. (2010) Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans. FEMS Yeast Research 10(2):199-208 (IF2.5)

20) Yu L, Zhao J, Feng J, Fang J, Feng C, Jiang Y, Cao Y, Jiang L* (2010) Candida albicans CaPTC6 is a functional homolog for Saccharomycese cerevisiae ScPTC6 and encodes a type 2C protein phosphatase. Yeast 27(4): 197–206 (IF2.0)

21) Zhao J, Sun X, Fang J, Liu W, Feng C, Jiang L* (2010) Identification and characterization of the type 2C protein phosphatase Ptc4p in the human fungal pathogen Candida albicans. Yeast 27(3):149-157 (IF2.0)

22) Wang X, Cui Y, Fan F, Song Y, Ren J, Meng Q, Xu W, Jiang L* (2010) Phylogenetic, carbendazim sensitivity and mycotoxin genotype analyses of Fusarium graminearum complex species isolated from wheat Fusarium head blight in China. Journal of Phytopathology 158:576–578 (IF1.0)

23) Zhang D, Fan F, Yang J, Wang X, Qiu D, Jiang L*(2010) FgTep1p is linked to the PI3 kinase signaling pathway and plays a role in the virulence of Fusarium graminearum on wheat. Molecular Plant Pathology 11(4): 495–502 (IF3.9)

24) Jiang L*, Yang J, Fan F, Zhang D and Wang X. (2010) The Type 2C protein phosphatase FgPtc1p of the plant fungal pathogen Fusarium graminearum is involved in lithium toxicity and virulence. Molecular Plant Pathology 11(2): 277-282 (IF3.9)

25) Fan J, Wu M, Jiang L, Shen SH (2009) A serine/threonine protein phosphatase-like protein, CaPTC8, from Candida albicans defines a new PPM subfamily. Gene 430(1-2):64-76 (IF2.2)

26) Li X, Huang X, Zhao J, Zhao J, Wei Y and *Jiang L (2008) The MAP kinase-activated protein kinase Rck2p plays a role in rapamycin sensitivity in Saccharomyces cerevisiae and Candida albicans. FEMS Yeast Research 8(5):715-724 (IF2.5)

27) Wan Y, Wang X, Huang Y, Qiu D and *Jiang L (2008) Identification and characterization of cDNA sequences encoding the HIS3 and LEU2 genes of the fungus Alternaria tenuissima. Journal of Genetics and Genomics 35(4):251-256 (IF2.1)

奖项

1) 2008年中国药学会科学技术奖二等奖

2) 2012年无锡市事业单位领军人才

3) 2013年江苏省双创人才

专利

1) 蒋伶活。酿酒酵母缺失菌株及其在耐糠醛方面的应用(专利号:ZL201210060827.2)

2) 蒋伶活,吕玮,段宏泉。1-(4-羟基-3-甲氧基笨基)-7-(4-羟苯基)-3,5-二羟基庚烷的用途(抗病原真菌-白念珠菌活性)(专利号:ZL200610014485.5)

3) 蒋伶活,吕玮,段宏泉。5-羟基1-(4-羟苯基)-7-苯基-3-庚酮的用途(抗病原真菌-白念珠菌活性) (专利号:ZL 200610014401.8)

4) 蒋伶活,吕玮,段宏泉。7-(4-羟苯基)-1-苯基-4-烯-3-庚酮的用途(抗病原真菌-白念珠菌活性) (专利号:ZL200610014400.3)

5) 刘立明, 徐国强, 段宁骏, 庄洪波, 陈坚. 一种产延胡索酸的酿酒酵母基因工程菌及其构建方法和应用. 授权公告号: ZL201010559061.3

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