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    个人信息

    夏海锋

    证件照 20130901

    夏海锋

    出生日期

    1979.12

    副教授

    0510-85197123

    0510-85197123

    E-mail

    hfxia@jiangnan.edu.cn

    教育经历:
        1999-2003年,中国药科大学,生物工程专业获得工学学士学位

    2003-2008年,浙江大学,化学工程与生物工程系,生物化工专业获得工学博士学位

    工作经历:
    2008-2011年,江南大学,生物工程学院,副教授

    2012年至今,江南大学,粮食发酵工艺与技术国家工程实验室,副教授

    201311-201412月,美国俄亥俄州立大学,化工系,博士后访问学者

    学术兼职:

    研究方向:

    生物分离技术及发酵工程技术

    主要在研项目:

    1、 基于Npu DnaE断裂内含肽的自我剪切型亲和纯化标签和纯化系统的基础研究( BK20151123),江苏省自然科学基金面上研究项目

    2、 疏水电荷诱导型高效液相色谱机制及应用研究(21206054/B060802),国家自然科学基金

    3、 生物过程关键技术及装备开发之课题生物制造反应过程技术与装备 2012AA021201),国家十二五”“863” 生物和医药领域工业生物技术的主题项目

    4、 解淀粉芽孢杆菌3-羟基丁酮和2,3-丁二醇可逆代谢机制及调控策略(20110093120001),教育部高等学校博士学科点专项科研基金

     

    研究生招生专业:

    发酵工程,生物工程专硕,轻工技术与工程专硕

    代表性学术成果(论文、专利等):

    论文:

    [1] Hai-Feng Xia*, Bin-Bin Don, Meng-Jie Zheng. Mixed-mode chromatography integrated with high-performance liquid chromatography for protein analysis and separation: Using bovine serum albumin and lysozyme as the model target. Journal of Separation Science. 2016, 39, 1900-1907

    [2] Hai-Feng Xia*, Zhen-Dong Liang, Pu-Qiang Wu, Sha-Li Wang, Xiong-Hua Jin. Molecular modification of protein A to improve the elution pH and alkali-resistance in affinity chromatography. Applied Biochemistry and Biotechnology. 2014, 172:4002-4012

    [3] Hai-Feng Xia*, Sha-Li Wang, Xiong-Hua Jin, Zhen-Dong Liang. Characteristics and application of porous ceramic/agarose composite beads derived as an affinity medium. Chromatographia. 2014, 77: 25-30

    [4] Yong-Mei Cheng, Xiong-Hua Jin, Dong Gao, Hai-Feng Xia*, Jing-Hua Chen. Thermodynamics and kinetics of lysozyme adsorption onto two kinds of weak cation exchangers.Biotechnology and Bioprocess Engineering. 2013, 18(5): 950-955

    [5] Hai-Feng Xia, Dong-Qiang Lin, Zhen-Ming Chen, Shan-Jing Yao. Purification of immunoglobulin of egg yolk with hydrophobic charge induction chromatography: comparison of operation modes with packed bed and expanded bed. Separation Science and Technology. 2012, 47(16), 2366-2372.

    [6] Hai-Feng Xia*, Xiong-Hua Jin, Pu-Qiang Wu, Zhi-Yong Zheng. Porous ceramic/agarose composite adsorbents for fast protein liquid chromatography. Journal of Chromatography A, 2012, 1223: 126-130

    [7] Hai-Feng Xia, Dong-Qiang Lin, Zhen-Ming Chen, Shan-Jing Yao. Influences of ligand structure and pH on the adsorption with hydrophobic charge induction adsorbents: a case study of antibody IgY. Separation Science and Technology. 2011, 46: 1957-1965.

    [8] Hai-Feng Xia, Dong-Qiang Lin, Zhen-Ming Chen, Shan-Jing Yao. Salt-promoted adsorption of an antibody onto hydrophobic charge-induction adsorbents. Journal of Chemical & Engineering Data. 2010, 55: 5751–5758

    [9] Hai-Feng Xia, Dong-Qiang Lin, Shan-Jing Yao. Chromatographic performance of macroporous cellulose-tungsten carbide composite beads as anion exchanger for expanded bed adsorption at high operation velocity. Journal of Chromatography A, 2008, 1195:60-66

    [10] Hai-Feng Xia, Dong-Qiang Lin, Li-Ping Wang, Shan-Jing Yao. Preparation and evaluation of cellulose adsorbents for hydrophobic charge induction chromatography. Industrial & Engineering Chemistry Research, 2008, 47: 9566-9572

    [11] Hai-Feng Xia, Dong-Qiang Lin, Shan-Jing Yao. Preparation of macroporous cellulose-tungsten carbide composite beads for expanded bed applications and its characteristics. Journal of Chromatography A, 2007, 1175: 55-62

    [12] Hai-Feng Xia, Dong-Qiang Lin, Shan-Jing Yao. Evaluation of new high-density ion exchange adsorbents for expanded bed adsorption chromatography. Journal of Chromatography A, 2007, 1145: 58-66

    [13] Hai-Feng Xia, Dong-Qiang Lin, Shan-Jing Yao. Spherical cellulose-nickel powder composite matrix customized for expanded bed application. Journal of Applied Polymer Science, 2007, 104: 740-747

     

    专利:

     

    [1] 夏海锋;金雄华;吴璞强;郑梦杰. 一种新型高效液相色谱介质及其制备方法. 201210003448.X

    [2] 夏海锋;吴璞强;金雄华;郑梦杰. 一种多孔陶瓷微球的孔道扩增方法. 201210003433.3

    [3] 夏海锋;吴璞强;梁振东;王沙莉;郑梦杰. 一种性能改进的重组蛋白A亲和配基及其构建方法201310097553.9

    [4] 夏海锋;王沙莉;毛银. 一种菌株其诱变方法及其发酵生产脂肪酶的方法. 201510138204.6

    [5] 夏海锋;李子武;朱胜杰. 一种去除污水中COD的微生物菌剂及其制备方法与应用. 201610389709.4

    [6] 夏海锋;李子武;朱胜杰. 一种微生物菌剂及其制备方法与应用. 201610389710.7

    [7] 夏海锋;王姝婧;王玉君. 亲和配基、构建方法、亲和层析介质、制备方法及应用. 201610749025.0

    [8] 夏海锋;王沙莉;梁振东;郑梦杰. 一种凝胶微球喷射装置. 201320529198.3

    [9] 夏海锋;王沙莉;梁振东. 一种蛋清溶菌酶生产线中的脱盐系统. 201320531230.1

     

    获奖及荣誉:

    [1] 姚善泾,林东强,关怡新,贠军贤,夏海锋,高栋,靳挺.扩张床吸附介质研制及生物分离机制研究.浙江省科学技术奖二等奖.2010

    资料更新日期:201610

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