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副教授

陆震鸣

编辑: 发布日期:2017-11-08 来源:
职称 副教授 研究方向 传统发酵食品微生态研究、药食用真菌生物技术、微生物催化技术

 

                       

姓 名:陆震鸣

性 别:男

出生日期:1981.11

职 称:副教授、硕士生导师

电 话:0510-85910116

E-mail:zhenming_lu@163.com

教育经历:

2000.09-2004.06 江南大学,生物工程专业,工学学士

2004.09-2006.06 江南大学,微生物与生化药学专业,医学硕士

2006.09-2009.12 江南大学,发酵工程专业,工学博士

工作经历:

2010年11月至今江南大学粮食发酵工艺与技术国家工程实验室,副教授

2010.01-2016.10 江南大学药学院,副教授

2014.03-2014.11 英国谢菲尔德大学工程学院,访问学者

2014.12-2015.02 英国牛津大学工程学院,访问学者

研究方向:

传统发酵食品微生态研究

药食用真菌生物技术

微生物催化技术

主要在研项目:

1. 国家自然科学基金青年基金(31401931), 2015-2017,主持

2. 国家重点研发计划项目子课题(2016YFD0400505-02), 2016-2020,主持

3. 国家自然科学基金重点项目子课题(31530055), 2016-2020,主持

研究生招生专业:

发酵工程、药学(微生物与生化药学)、制药工程

代表性学术成果:

近年来以主要作者发表科研论文70余篇(SCI收录45篇)。代表性论文如下:

传统发酵食品微生态研究

1.Lu ZM, Wang ZM, Zhang XJ, et al. Microbial ecology of cereal vinegar fermentation: insights for driving the ecosystem function.Current Opinion in Biotechnology. 2018 49:88-93.

2. Xiao C,Lu ZM, Zhang XJ, et al. Bio-heat is a key environmental diver shaping the microbial community of medium-temperature Daqu.Applied and Environmental Microbiology, 2017, 83

3.Lu ZM, Liu N, Wang LJ, et al. Elucidating and regulating the acetoin production role of microbial functional groups in multispecies acetic acid fermentation.Applied and Environmental Microbiology, 2016, 82: 5960-5868.

4. Wu LH,Lu ZM, Zhang XJ, et al. Metagenomics reveals flavour metabolic network of cereal vinegar microbiota.Food Microbiology, 2017, 62: 23-31. (co-first author)

5. Wang ZM,Lu ZM, Shi JS, Xu ZH. Exploring flavour-producing core microbiota in multispecies solid-state fermentation of traditional Chinese vinegar.Scientific Reports, 2016, 6: 26818. (co-first author)

6. Wang ZM,Lu ZM, Yu YJ, et al. Batch-to-batch uniformity of bacterial community succession and flavor formation in the fermentation of Zhenjiang aromatic vinegar.Food Microbiology, 2015, 50: 64-69.

7. Yu YJ,Lu ZM, Yu NH, et al. HS-SPME/GC-MS and chemometrics for volatile composition of Chinese traditional aromatic vinegar in the Zhenjiang region.Journal of the Institute of Brewing, 2012, 118: 133-141.

8. Xu W, Huang ZY, Zhang XJ, Li Q,Lu ZM, et al.Monitoring the microbial community during solid-state acetic acid fermentation of Zhenjiang aromatic vinegar.Food Microbiology, 2011, 28: 1175-1181.

9.Lu ZM, Xu W, Yu NH, et al.Recovery of aroma compounds from Zhenjiang aromatic vinegar by supercritical fluid extraction.International Journal of Food Science and Technology, 2011, 46: 1508-1514.

10.陆震鸣,敖宗华,易彬,张宿义,沈才洪,许正宏.我国传统固态发酵食品工业现状和技术发展趋势.2012工业生物技术发展报告,科学出版社, 245-252.

药食用真菌生物技术

1.Lu ZM, Zhu Q, Li HX, et al. Vanillin promotes germination ofAntrodia camphorataarthroconidia through PKA and MAPK signaling pathway.Frontiers in Microbiology, 2017, 8: 2048.

2. Li HX,Lu ZM, Zhu Q, et al. Comparative transcriptomic and proteomic analyses reveal a FluG-mediated signalling pathway relating to asexual sporulation ofAntrodia camphorata.Proteomics, 2017, 17: 1700256. (co-first author)

3. Geng Y, Wang J, Sun Q, Xie MF,Lu ZM, et al. Identification of antrodin B fromAntrodia camphorataas a new anti-hepatofibrotic compound using a rapid cell screening method and biological evaluation.Hepatology Research, 2016, 43: E15-E25.

4. Li HX,Lu ZM, Geng Y, et al. Efficient production of bioactive metabolites fromAntrodia camphorataATCC 200183 by asexual reproduction-based repeated batch fermentation.Bioresource Technology, 2015, 194: 334-343.

5.Lu ZM, He Z, Li HX, et al. Modified arthroconidial inoculation method for the efficient fermentation ofAntrodia camphorataATCC 200183.Biochemical Engineering Journal, 2014, 87: 41-49.

6.Lu ZM, Geng Y, Li HX, Sun Q, Shi JS, Xu ZH. Alpha-terpineol promotes triterpenoid production ofAntrodia cinnamomeain submerged culture.FEMS Microbiology Letters, 2014, 358: 36-43.

7. Geng Y,Lu ZM, Huang W, et al. Bioassay-guided isolation of DPP-4 inhibitory fractions from extracts of submerged cultured ofInonotus obliquus.Molecules, 2013, 18: 1150-1161. (co-first author)

8.Lu ZM, Lei JY, Xu HY, et al. Optimization of fermentation medium for triterpenoid production fromAntrodia camphorataATCC 200183 using artificial intelligence-based techniques.Applied Microbiology and Biotechnology, 2011, 92:371-379

9.Lu ZM, Tao WY, Xu HY, et al. Analysis of volatile compounds ofAntrodia camphoratainsubmerged culture using headspace solid-phase microextraction.Food Chemistry, 2011, 127: 662-668.

10.Lu ZM, Tao WY, Xu HY, et al. Further studies on the hepatoprotective effect ofAntrodia camphoratain submerged culture on ethanol-induced acute liver injury in rats.Natural Product Research, 2011, 25: 684-695.

11.Lu ZM, Xu ZH. Antcin A contributs to anti-inflammatory effect ofNiuchangchih(Antrodia camphorata).Acta Pharmacologica Sinica, 2011, 32, 981-982.

12. Ao ZH, Xu ZH,Lu ZM, et al.Niuchangchih(Antrodia camphorata) and its potential in treating liver diseases.Journal of Ethnopharmacology, 2009, 121: 194-212.

13.Lu ZM, Tao WY,Zou XL,et al. Protective effects of mycelia ofAntrodia camphorataandArmillariella tabescensin submerged culture against ethanol-induced hepatic toxicity in rats.Journal of Ethnopharmacology, 2007, 110: 160-164.

微生物催化技术

1. Dong TT, Gong JS, Gu BC, Zhang Q, Li H,Lu ZM, et al. Significantly enhanced substrate tolerance ofPseudomonas putidanitrilase via atmospheric and room temperature plasma and cell immobilization.Bioresource Technology, 2017, 244: 1104-1110.

2. Gong JS, Li H,Lu ZM, et al.Engineering of a fungal nitrilase for improving catalytic activity and reducing by-product formation in the absence of structural information.Catalysis Science & Technology, 2016, 6: 4134.

3. Gong JS, Shi JS,Lu ZM, et al. Nitrile-converting enzymes as a tool to improve biocatalysis in organic synthesis: recent insights and promises.Critical Reviews in Biotechnology, 2015, 23: 1-13.

4. Gong JS, Li H,Lu ZM, et al. Recent progress in the application of nitrilase in the biocatalytic synthesis of pharmaceutical intermediates.Progress in Chemistry, 2015, 2015, 27: 448-458.

5. Gong JS,Lu ZM, Li H, et al. Metagenomic technology and genome mining: emerging areas for exploring novel nitrilases.Applied Microbiology and Biotechnology, 2013, 97: 6603-6611.

6. Gong JS,Lu ZM, Li H, et al. Nitrilases in nitrile biocatalysis: Recent progress and forthcoming research.Microbial Cell Factory, 2012, 11: 142. (co-first author)

近年合作申请国家发明专利62件,已获授权28件。主要专利:

1. 酒醅微生物群落中中乳酸菌、梭菌、芽孢杆菌的定量分析.专利号: ZL201410120323.4

2. 大曲微生物群落中乳酸菌和芽孢杆菌的定量分析方法.专利号: ZL2014101193976

3. 一种樟芝无性孢子低温保藏保护剂及其使用方法.专利号: ZL2013106777565

4. 一种基于无性孢子的樟芝快速液态发酵工艺.专利号: ZL201110053317.8

5. 一种用于固态酿造食醋发酵过程的生物强化技术.专利号: ZL201110116235.3

6. 一株枯草芽孢杆菌及其应用.专利号: ZL20101029731.2

7. 一株短小芽孢杆菌及其应用.专利号: ZL201010297112.X

8. 一株高产细菌纤维素的耐高温中间葡糖醋杆菌.专利号: ZL2013106786085

9. 高产甘氨酸菌株的筛选及其在腈类化合物转化中的应用.专利号: ZL2010105671502

10. 一种基于液体深层发酵的樟芝无性孢子的制备方法及其应用.申请号: 201110053305.5

获奖及荣誉:

1. 江苏省科学技术奖一等奖, 2014,排名3

2. 全国商业联合会科技进步奖一等奖, 2009,排名5

上一篇:李由然

技术支持:信息化建设与管理中心

地址:江苏省无锡市蠡湖大道1800号

邮编:214122

联系电话:0510-85328539

服务邮箱:nelcft@jiangnan.edu.cn